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Structure Determination

  • The structure of a crystalline solid can be determined using X-ray diffraction.

  • X-rays from an X-ray tube are directed through a collimator at a crystal.

  • The X-rays interact with the electron clouds of the atoms and diffract because the wavelength of the X-rays is about the same magnitude as the spacing between atoms.

  • Photographic film can be used to detect the diffracted X-rays.

  • The experiment can be scaled up by factors of thousands: diffraction can be illustrated using visible laser light, an array of laser-written, photographically-reduced dots on a 35-mm slide, and a projection screen.