JCE 92.05—May 2015 Issue Highlights

Journal of Chemical Education May 2015 Cover

Teaching the Relevance of Chemistry

The May 2015 issue of the Journal of Chemical Education is now available online to subscribers. This issue includes articles on drugs & pharmaceuticals; health; food; plants; exploring viscosity; new approaches to teaching organic chemistry; computer-assisted learning; scents & flavors.


In What Do Editors Do All Day?, Norbert J. Pienta discusses some of the duties, responsibilities, and activities of the editor-in-chief in anticipation of the process to find the next editor of JCE.

Award Address

The precollege section of JCE has begun video recording interviews of ACS James Bryant Conant Awardees. In High School Chemistry’s Leading Lady, Deanna Cullen interviews award-winner Kathy Kitzmann of Michigan.

Drugs & Pharmaceuticals

Cover In An Integrated Approach to Thermal Analysis of Pharmaceutical Solids, Shelley R. Rabel Riley describes an experiment in which undergraduate instrumental analysis students elucidate the nature of thermal transitions for active pharmaceutical ingredients and excipients using differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and thermal microscopy.

Letter Comment on “Purity Analysis of the Pharmaceuticals Naproxen and Propranolol: A Guided-Inquiry Laboratory Experiment in the Analytical Chemistry Laboratory” ~ Alan M. Rosan

Book Review Review of In Retrospect: From the Pill to the Pen ~ Robert E. Buntrock


The Khat and Meow Meow Tale: Teaching the Relevance of Chemistry through Novel Recreational Drugs ~ Suzanne Fergus, Kathryn Kellett, and Ute Gerhard

Metalloprotease Peptide Inhibitors: A Semester-Long Organic Synthetic Research Project for the Introductory Laboratory Course ~ Jason K. Pontrello

Distributed Drug Discovery: Advancing Chemical Education through Contextualized Combinatorial Solid-Phase Organic Laboratories ~ William L. Scott, Ryan E. Denton, Kathleen A. Marrs, Jacob D. Durrant, J. Geno Samaritoni, Milata M. Abraham, Stephen P. Brown, Jon M. Carnahan, Lindsey G. Fischer, Courtney E. Glos, Peter J. Sempsrott, and Martin J. O’Donnell

Using Free Computational Resources To Illustrate the Drug Design Process in an Undergraduate Medicinal Chemistry Course ~ Ricardo P. Rodrigues, Saulo F. Andrade, Susimaire P. Mantoani, Vera L. Eifler-Lima, Vinicius B. Silva, and Daniel F. Kawano

A Prospective Method To Guide Small Molecule Drug Design ~ Alan T. Johnson

Laboratory Experiments

Exploring Drug Diffusion through a Membrane: A Physical Chemistry Experiment for Health and Life Sciences Undergraduate Students ~ Isabel A. C. Ribeiro, Célia M. C. Faustino, Rita C. Guedes, António J. I. Alfaia, and Maria H. L. Ribeiro

Fighting Tuberculosis in an Undergraduate Laboratory: Synthesizing, Evaluating and Analyzing Inhibitors ~ David Daniels, Charlotte Berkes, Arjan Nekoie, and Jimmy Franco


Chemical Education Research Community-Based Inquiry in Allied Health Biochemistry Promotes Equity by Improving Critical Thinking for Women and Showing Promise for Increasing Content Gains for Ethnic Minority Students ~ Terrah J. Goeden, Martha J. Kurtz, Ian J. Quitadamo, and Carin Thomas

Article Quantitative Analysis of Heavy Metals in Children’s Toys and Jewelry: A Multi-Instrument, Multitechnique Exercise in Analytical Chemistry and Public Health ~ Lauren E. Finch, Margot M. Hillyer, and Michael C. Leopold

Activity Playing an Electron Transport System Game to Improve Health Students’ Learning ~ Colleen Conway and Maureen Leonard

Laboratory Experiment Determination of Niacinamide in Lotions and Creams Using Liquid–Liquid Extraction and High-Performance Liquid Chromatography ~ Karyn M. Usher, Carolyn R. Simmons, Daniel W. Keating, and Henry F. Rossi, III


Activity Using Internet Databases for Food Science Organic Chemistry Students To Discover Chemical Compound Information ~ Piotr Minkiewicz, Anna Iwaniak, and Małgorzata Darewicz

Demonstration A Qualitative Analysis of Sulfite Ions in White Wine Based on Visible Color Changes ~ Natalie Chiaverini and Tom Mortier

Laboratory Experiments

Computational Chemistry Laboratory: Calculating the Energy Content of Food Applied to a Real-Life Problem ~ Dora Barbiric, Lorena Tribe, and Rosario Soriano

Integration of Nanoparticle-Based Paper Sensors into the Classroom: An Example of Application for Rapid Colorimetric Analysis of Antioxidants ~ Erica Sharpe and Silvana Andreescu

Identification and Analysis of Bioactive Components of Fruit and Vegetable Products ~ Francis M. Mann

Phospholipids, Dietary Supplements, and Chicken Eggs: An Inquiry-Based Exercise Using Thin-Layer Chromatography ~ Sara E. Potteiger and Julie M. Belanger

Separation of Caffeine from Beverages and Analysis Using Thin-Layer Chromatography and Gas Chromatography–Mass Spectrometry ~ Janelle L. Torres y Torres, Shauna L. Hiley, Steven P. Lorimor, Jonathan S. Rhoad, Benjamin D. Caldwell, Gerald L. Zweerink, and Michael Ducey

Simultaneous Determination of Pyridoxine and Riboflavin in Energy Drinks by High-Performance Liquid Chromatography with Fluorescence Detection ~ P. Martí-Andrés, L. Escuder-Gilabert, Y. Martín-Biosca, S. Sagrado, and M.J. Medina-Hernández

Laboratory Production of Lemon Liqueur (Limoncello) by Conventional Maceration and a Two-Syringe System To Illustrate Rapid Solid–Liquid Dynamic Extraction ~ Daniele Naviglio, Domenico Montesano, and Monica Gallo

Plant Experiments

Determination of Plant Volatiles Using Solid Phase Microextraction GC–MS ~ Scott Van Bramer , Katherine R. Goodrich

Using a Microscale Approach To Rapidly Separate and Characterize Three Photosynthetic Pigment Species from Fern ~ Theppawut Israsena Na Ayudhya, Frederick T. Posey, Jessica C. Tyus, and Nin N. Dingra

Studying Viscosity in the Laboratory

Introducing Students to Rheological Classification of Foods, Cosmetics, and Pharmaceutical Excipients Using Common Viscous Materials ~ Célia Faustino, Ana F. Bettencourt, António Alfaia, and Lídia Pinheiro

The Rheological Properties of Poly(vinyl alcohol) Gels from Rotational Viscometry ~ Glenn A. Hurst, Malika Bella, and Christoph G. Salzmann

Effects of Metal Ions on Viscosity of Aqueous Sodium Carboxylmethylcellulose Solution and Development of Dropping Ball Method on Viscosity ~ Seng Set, David Ford, and Masakazu Kita

New Approaches to Teaching Organic Chemistry

Student Response to a Partial Inversion of an Organic Chemistry Course for Non-Chemistry Majors ~ Kathleen S. Rein and David T. Brookes

Mechanisms before Reactions: A Mechanistic Approach to the Organic Chemistry Curriculum Based on Patterns of Electron Flow ~ Alison B. Flynn and William W. Ogilvie

Computer-Assisted Learning

A Comprehensive Application To Assist in Acid–Base Titration Self-Learning: An Approach for High School and Undergraduate Students ~ David González-Gómez, Diego Airado Rodríguez, Florentina Cañada-Cañada, and Jin Su Jeong

Using Least Squares for Error Propagation ~ Joel Tellinghuisen

The Simulation of an Oxidation–Reduction Titration Curve with Computer Algebra ~ Richard V. Whiteley, Jr.

From the Archives: Scents and Flavors

In Using Flavor Chemistry To Design and Synthesize Artificial Scents and Flavors, Jessica L. Epstein, Michael Castaldi, Grishma Patel, Peter Telidecki, and Kevin Karakkatt describe an activity in which students are given an overview of flavor chemistry and design a product (soap or candle). Other resources from past issue of the Journal for exploring scents and flavors and making soap include:

Discovering Scents & Flavors

The Chemistry of Perfume: A Laboratory Course for Nonscience Majors ~ Jennifer L. Logan and Craig E. Rumbaugh

The Chemistry of Fragrances: A Group Exercise for Chemistry Students ~ Nigel D. Lowe, Roger Duprey, and Charles S. Sell

Olfactory Delights ~ Marilyn C. Sbrollini

The Nature of Essential Oils. I. Production; II. Chemical Constituents, Analysis ~ Frances S. Sterrett

JCE Classroom Activity: Apple Fool! An Introduction to Artificial Flavors ~ JCE staff

Application: Making Soap

Making Usable, Quality Opaque or Transparent Soap ~ Suzanne T. Mabrouk

JCE Classroom Activity: Soapmaking ~ JCE staff

92 Volumes of Writing on Chemistry

In his Commentary, Reuben Hudson discusses Similarities between Scientific and Dramatic Prose. This serves as a reminder that writing and communicating ideas are at the heart of JCE (and we mourn the recent loss of William Zinsser, author of the book On Writing Well in which he encouraged writers to “simplify your language and thereby find your humanity”). If you are considering writing an article for JCE, there are numerous author resources available on JCE’s ACS Web site, including recently updated:

Author Guidelines

Document Templates

Reference Guidelines

With 92 volumes of the Journal of Chemical Education to explore, you will always find something useful—including all of the articles mentioned above, and many more, in the Journal of Chemical Education. Articles that are edited and published online ahead of print (ASAP—As Soon As Publishable) are also available.